WARNING: This product contains nicotine. Nicotine is an addictive chemical.

Electronic Cigarettes (E-Cigs) are intended for adult use only. They are not intended to diagnose, treat, cure or prevent any disease. Additionally, E-Cigs are not recognized by the Food and Drug Administration (FDA) as a tobacco harm reduction tool or a tobacco cessation device.

California Prop 65 Warning: This product can expose you to chemicals, including nicotine, which are known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, go to: www.P65Warnings.ca.gov

The opinions expressed in referenced articles and studies are the authors’ own and do not reflect the opinion of  Vandalia Mist Extracts & Vapors, LLC (DBA Vandalia Mist).

 

What are Electronic Cigarettes?

E-cigs come in many shapes and sizes and are used as an alternative nicotine delivery method. Unlike traditional cigarettes, e-cigs do no utilize combustion, so there is no smoke. Instead, an e-liquid solution that contains four basic ingredients – all of which are already approved for use in foods, cosmetics and medications, is heated by a simple battery, producing a vapor. The user inhales the vapor to deliver a specific concentration of nicotine, from zero to 2.4 percent, with the most common usage being 0.3 percent nicotine solution.

 

How are E-Liquids Made?

 

 

 

 

 

 

American Cancer Society 2018 position on E-Cigs

Scientific Summary: Based on currently available evidence, using current generation e-cigarettes is less harmful than smoking cigarettes, but the health effects of long-term use are not known.

https://www.cancer.org/healthy/stay-away-from-tobacco/e-cigarette-position-statement.html

2018 Studies:

1. New study from Public Health England confirms 2015 claim that vaping is 95 percent less harmful than smoking, three years after their first landmark study. They also find that never smokers make up less than one percent of vapers. Importantly, both the adult and teen smoking rate continues to decline.

https://www.dropbox.com/sh/1ie2axkwcpr7v3n/AACkB6NC4VXPKSQQMFCzgaWAa?dl=0&preview=Evidence+review+of+e-cigarettes+and+heated+tobacco+products+2018+executive+summary.pdf

 

E-cigarettes v cigarettes

Our animation shows the difference between e-cigarettes and cigarettes. We have published a new evidence update on e-cigarettes, and you can read more about it in our blog: http://bit.ly/2nFVkSB

Posted by Public Health England on Tuesday, February 6, 2018

2. National Academies of Science, Engineering and Medicine landmark study used existing research up to August 31, 2017 to determine the effect of  E-Cigs on public health. The complex balance between adult smoker harm reduction and youth initiation must be examined carefully. More studies are needed to best determine how to proceed.

http://www.nationalacademies.org/hmd/reports/2018/public-health-consequences-of-e-cigarettes.aspx

3. NYU finds e-cigs are 95 percent less harmful than traditional combustible cigarettes and should be promoted as a harm-reduction tool for smokers while also setting policy to deter youth initiation of smoking.

http://www.annualreviews.org/doi/pdf/10.1146/annurev-publhealth-040617-013849

2017 Studies:

1. Georgetown Lombardi Cancer Center research finds switching to vaping could save 6.6 million US lives in ten years

– https://gumc.georgetown.edu/news/Tobacco_Smokers_Could_Gain_86%20Million_Years_of_Life_if_they_Switch_to_Vaping_Study_Finds

 

2. ND University, Chicago, IL study finds vaping does not increase likelihood of later smoking

– https://www.ncbi.nlm.nih.gov/labs/articles/28841780/

 

3. Yale/NBER paper finds banning flavors would increase smoking of combustibles

– http://www.nber.org/papers/w23865

 

4. CDC Finds More Smokers Use Vaping to Quit Than Any FDA-approved Method in 2017

Table 1. Prevalence of Any Quit Method Used (Alone or in Combination With Any of the Other 9 Quit Methodsa) During the Most Recent Quit Attempt Among US Adult Cigarette Smokers Who Tried to Quit in the Previous 3 Months (n = 15,943), 2014–2016
Quit Method Useda No. (Weighted %b)
Reported using multiple quit methods 12,417 (74.7)
Gave up cigarettes all at once 10,631 (65.3)
Gradually cut back on cigarettes 9,682 (62.0)
Substituted some regular cigarettes with e-cigarettes 5,861 (35.3)
Used nicotine patch or nicotine gum 4,047 (25.4)
Switched completely to e-cigarettes 3,721 (24.7)
Switched to “mild” cigarettes 3,376 (20.4)
Got help from a doctor or other health professional 2,963 (15.2)
Used FDA-approved medications such as Zyban or Chantix 2,374 (12.2)
Got help from a website such as Smokefree.gov 1,146 (7.1)
Got help from a telephone quitline 853 (5.4)

Abbreviation: FDA, US Food and Drug Administration.
a Respondent was permitted to select one or more of the 10 quit-method categories used in his or her most recent quit attempt; thus, categories are not mutually exclusive. Estimates are for those who used 2 or more quit methods (combined) and those who used only one.
b Percentages were based on a denominator of 15,943 and were weighted to reflect national distributions of sex, age, race/ethnicity, and education among cigarette smokers.

5. State of California studies vapor and finds “secondhand vaping” appears to result in minimal exposure of bystanders to hazardous chemicals. Study published April 2017.

http://tobaccoanalysis.blogspot.com/2017/05/vape-shop-air-sampling-by-california.html

6. Cancer Research UK: Long-term e-cigarette–only use is associated with substantially reduced levels of measured carcinogens and toxins compared to smoking combustible cigarettes. Study published Feb. 2017.

http://annals.org/aim/article/2599869/nicotine-carcinogen-toxin-exposure-long-term-e-cigarette-nicotine-replacement

 

7. 2017 British study finds smokers who switch to vaping reduce toxins.

http://www.sandiegouniontribune.com/business/biotech/sd-me-vaping-safety-20170206-story.html

 

8. Boston University study finds there is no gateway of e-cigs to addict youth. Published Jan. 2017

http://tobaccocontrol.bmj.com/content/25/Suppl_1/i90.full#block-system-main

 

9. Oxford University study finds that e-cigs can keep children from exposure to dangerous smoke. Published Jan. 2017

https://academic.oup.com/her/article-abstract/doi/10.1093/her/cyw052/2901800/Using-e-cigarettes-in-the-home-to-reduce-smoking

 

10. Center for Addictions Research at University of Victoria (B.C.) finds that e-cigs are replacing smoking, not encouraging smoking. They also found that e-cig vapor is less harmful, containing only trace amounts of some chemicals found in cigarette smoke at much higher levels. Published Jan. 2017

http://www.uvic.ca/research/centres/carbc/assets/docs/report-clearing-the-air-review-exec-summary.pdf

 

 

 

New Legislation:

Congressman Duncan Hunter (R-CA) introduced repeal and replace legislation for the vaping industry in April, 2017. The Cigarette Smoking Reduction and Electronic Vapor Alternatives Act is designed to offer reasonable regulation and harm-reduction strategies moving forward. Click to learn more.

Freedom Factor | U.S. Rep. Duncan Hunter Talks New Vaping Legislation

 

Overview: Comprehensive Rolling Stone Dec. 2015 article on e-cigs.

http://www.rollingstone.com/politics/news/e-cigs-inconvenient-truth-its-much-safer-to-vape-20151221

 

Are e-cigs safe?

Any substance inhaled into the lungs is not 100 percent safe. However, recent studies have found that e-cigs are 95 percent less harmful than traditional combustion cigarettes. Tobacco addiction specialists are beginning to point out the difference between nicotine and smoking since mounting evidence shows it’s the smoke that kills, not the nicotine.

The landmark 2015 Public Health England comprehensive study on e-cigs found they are 95 percent less harmful than traditional cigarettes.

http://www.reuters.com/article/us-health-britain-ecigarettes-idUSKCN0QN2AC20150818

The first long-term study of e-cig users here in the US showed that vapers who had been smoke-free for three years had 61 percent of smoke-induced health ailments resolved and their risk for contracting other smoke-related disease dropped 94 percent.

 https://www.docdroid.net/zFXwl5b/ecigs-health-effects-r-cranfield-nov-24-2015.pdf.html

Nicotine has been found to have about the same qualities as caffeine in recent studies. It is being successfully used to treat cognitive ailments as well as nervous disorders. Note, the nicotine patch and nicotine gum are approved for over-the-counter use by the FDA.

http://www.medicaldaily.com/smoking-cigarettes-kills-nicotine-all-bad-333978

Myths about chemicals
present in e-cigs

 

The base ingredient for e-liquids is Propylene Glycol which is considered GRAS (generally recognizes as safe) by the FDA and EPA. This versatile substance is used in many foods, cosmetics, medicines and fog machines during stage performances. Other myths about e-liquids have also been debunked.

http://dailycaller.com/2016/03/05/formaldehyde-fears-used-to-smear-e-cigarettes-have-now-been-thoroughly-discredited/

http://www.sciencedirect.com/science/article/pii/S0273230015301549

Second-hand vapor is harmless

The most recent studies have found that second-hand vapor released from e-cigs is non-toxic and most comparable to indoor air, with virtually no nicotine present.

http://www.treatobacco.net/en/page_528.php

Can e-cigs help me quit smoking?

A 2015 CDC report found that 50 percent of people who gave up traditional cigarettes did it with e-cigs.

https://www.heartland.org/policy-documents/research-commentary-new-cdc-report-finds-vaping-helps-smokers-quit

A 2016 Mayo Clinic report found a high percentage of patients who were given e-cigs prior to surgery either quit smoking all together, or switched to e-cigs as a less harmful alternative.

http://www.cocktailnerd.com/mayo-clinic-reveals-results-of-a-ground-breaking-new-ecig-experiment/

2019 New England Journal of Medicine says E-Cigs are twice as effective as other cessation methods.


E-cigs outperform patches and gums in quit-smoking study

Jan 30, 2019

The British research, published Wednesday in the New England Journal of Medicine, could influence what doctors tell their patients and shape the debate in the U.S., where the Food and Drug Administration has come under pressure to more tightly regulate the burgeoning industry amid a surge in teenage vaping.

“We know that patients are asking about e-cigarettes and many doctors haven’t been sure what to say,” said Dr. Nancy Rigotti, a tobacco treatment specialist at Harvard Medical School who was not involved in the study. “I think they now have more evidence to endorse e-cigarettes.”

At the same time, Rigotti and other experts cautioned that no vaping products have been approved in the U.S. to help smokers quit.

Smoking is the No. 1 cause of preventable death worldwide, blamed for nearly 6 million deaths a year. Quitting is notoriously difficult, even with decades-old nicotine aids and newer prescription drugs. More than 55 percent of U.S. smokers try to quit each year, and only about 7 percent succeed, according to government figures.

Electronic cigarettes, which have been available in the U.S. since about 2007 and have grown into a $6.6 billion-a-year industry, are battery-powered devices that typically heat a flavored nicotine solution into an inhalable vapor.

Most experts agree the vapor is less harmful than cigarette smoke since it doesn’t contain most of the cancer-causing byproducts of burning tobacco. But there is virtually no research on the long-term effects of the chemicals in the vapor, some of which are toxic.

At the same time, there have been conflicting studies on whether e-cigarettes actually help smokers kick the habit. Last year, an influential panel of U.S. experts concluded there was only “limited evidence” of their effectiveness.

In the new study, researchers tracked nearly 900 middle-age smokers who were randomly assigned to receive either e-cigarettes or nicotine replacement products, including patches, gums and lozenges. After one year, 18 percent of e-cigarette users were smoke-free, versus 9.9 percent of those using the other products.

“Anything which helps smokers to avoid heart disease and cancer and lung disease is a good thing, and e-cigarettes can do that,” said Peter Hajek, study co-author and an addiction specialist at Queen Mary University of London.

The study was more rigorous than previous ones, which largely surveyed smokers about e-cigarette use. Participants in this experiment underwent chemical breath testing.

Smokers in the e-cigarette group received a $26 starter kit, while those in the nicotine-replacement group received a three-month supply of the product of their choice, costing about $159. Participants were responsible for buying follow-up supplies.

“If you have a method of helping people with smoking cessation that is both more effective and less costly, that should be of great interest to anyone providing health services,” said Kenneth Warner, a retired University of Michigan public health professor who was not involved in the study.

Several factors may have boosted the results: All the participants were recruited from a government smoking-cessation program and were presumably motivated to quit. They also received four weeks of anti-smoking counseling.

The researchers didn’t test e-cigarettes against new drugs such as Pfizer’s Chantix, which has shown higher rates of success than older nicotine-based treatments.

Funding for the study came from the British government, which has embraced e-cigarettes as a potential tool to combat smoking through state-run health services. Some of the authors have been paid consultants to makers of anti-smoking products.

U.S. health authorities have been more reluctant about backing the products, in part because of the long-term effects are unknown.

“We need more studies about their safety profile, and I don’t think anyone should be changing practice based on one study,” said Belinda Borrelli, a psychologist specializing in smoking cessation at Boston University.

The American Heart Association backed e-cigarettes in 2014 as a last resort to help smokers quit after trying counseling and approved products. The American Cancer Society took a similar position last year.

An editorial accompanying the study and co-written by Borrelli recommended e-cigarettes only after smokers have tried and failed to quit with FDA-approved products. Also, doctors should have a clear timeline for stopping e-cigarette use.

Borrelli noted that after one year, 80 percent of the e-cigarette users in the study were still using the devices. Nine percent of the participants in the other group were still using gums and other nicotine-replacement products.

No vaping company has announced plans to seek FDA approval of their products as a quit-smoking aid. Winning such an endorsement would require large studies that can take years and cost millions of dollars.

The FDA has largely taken a hands-off approach toward vaping. It has not scientifically reviewed any of the e-cigarettes on the market and has put off some key regulations until 2022. FDA Commissioner Scott Gottlieb has said he doesn’t want to over-regulate an emerging industry that could provide a safer option for adult smokers.

The delay has come under intense criticism amid an explosion in teenage vaping, driven chiefly by devices like Juul, which resembles a flash drive. Federal law prohibits sales to those under 18, but 1 in 5 high school students reported vaping last year, according to a government survey. It showed teenage use surged 78 percent between 2017 and 2018.

Matthew Myers of the Campaign for Tobacco-Free Kids noted that the British study used so-called tank-based e-cigarettes, which allow users to customize their flavors and nicotine levels. Those devices have largely been overtaken in the U.S. by Juul and similar devices that have prefilled nicotine cartridges, or pods. Any benefit of e-cigarettes depends on the individual product and how it is used, he said.

“It is a fundamental mistake to think that all e-cigarettes are alike,” Myers said. “And in the absence of FDA regulation, a consumer has no way of knowing if the product they are using has the potential to help them or not.”

Myers’ group is one of several anti-smoking organizations suing the FDA to immediately begin reviewing e-cigarettes.

Ian Armitage was skeptical about e-cigarettes as a way to stop smoking, saying he tried vaping several years ago but gave it up after experiencing twitching and shakes from nicotine withdrawal.

“I tried it for a whole month, but it just wasn’t doing it for me,” said Armitage, an audio-visual technician in Washington. “I still wanted a cigarette afterward.”

Armitage, who has smoked for 15 years, said he also tried nicotine patches but found they irritated his skin.

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